It really is super complex and like @terb said, something that you play with to find the sound you want. There’s basically tons of variations depending on what you are looking for, especially with EQ/preamp/OD pedals and where you put them. And like @JoshFossgreen says, for just getting down and playing and practicing, jamming and so on, really matters very little.
I edited my post above to elaborate a little, posted my original at 3am so sorry if it was a bit light on explanation 
Basically this is something you don’t need to worry about unless you want to. Even for gigging. I happen to love this stuff to death, but I’m weird that way, I was very into effects, sound programming and signal chains from my previous life as a synth player/programmer, and the types of music I like are heavily effected.