I recieved my M-Audio Midi Oxygen 49 MkV midi controller the other day and was having trouble connecting it to my DAW, I use Reaper, with any consistency. The sound would cut out, become garbled or just plain would not work every time.
I discovered that bluetooth was the problem. I was using bluetooth headphones and a bluetooth external speaker system. All I had to do was disable the bluetooth in windows, and reconnect my wired studio speakers and wired headset. All problems and inconsistent operation cleared up.
Not sure why this happened, and don’t really care, but I just wanted others to be aware that this could happen.