I’ll differ slightly from my learned colleagues here (probably no real surprise) 
When I think blues I think Gibson. Probably an ES but a Les Paul works too.
Add a basic, clean, bluesbreaker type over drive and you’re all set to tell everyone what was going through your mind when you “woke up this mornin”.
You could definitely make the blues work with these. It’s actually funny that I would recommend single coils here, I more often than not border on humbucker supremacy - I love the sound. Plenty of blues players use Les Pauls, despite Strats and Teles being famous for it.
Still I would likely go with a Strat or a Telecaster pickup configuration. Lots of great strats and superstrats out there. But there’s a lot to be said for that thick rich sound of an overdriven humbucker.
John Mayer certainly makes it work 
Lots of voicing controls for that too.
My guitar approach is / was this…
Which one do I like the looks of the most, and does NOT have any sort of “whammy bar” system that’s going to complicate tuning.
I spent months looking at styles and colors etc and picked one that I thought was good quality, sounded good when online folks played it, and, most importantly, I loved loved loved the look of.
It’s gotta compete with 24 basses and 14 saxes for my time.
But what moves you to want to pick it up.
Blues and Fender Strat is like saying Salt and Pepper.
But then the king of Blues BB King plays a Gibson ES-335.
Yup. BB King (ES) or Buddy Guy (Strat), there’s no wrong answer here. 
My brother - a very talented blues guitarist - has played Squier/Fender Strats, Ibanez Destroyers, Fender Teles, Les Pauls (specifically the Buckethead signature Les Paul), PRS, Charvel, even an Abasi for a while.
If I may sound pretentious for a moment, blues are a feeling, man. Whatever helps you express that bluesy feeling is where you should start.
I like the darker one. Yummo.
What I found looking at guitars (teles) and I’m no expert is each model is very different sounding.
The neck feel (for most at least) matters. It doesn’t for me but if it does for you in bass it will more so on guitar.
Agreed. That’s a nice looking guitar.
Pretty sure my next instrument will be a grey body color and a dark fretboard 
It’s more an ES-345 or an ES-355 but in reality he used various different guitars, not only one.
To answer about blues guitars : you can play blues with anything. At the old time, the guys used to play on Stella acoustic guitar, only for one reason : it was the cheapest intrument available.
The standard for electric blues is definitly a Strat, but you can use anything else if you want. Something a bit rustic (let’s say “vintage style”) may be better.
I didn’t know that and that he maned all his guitars “Lucille”. I always thought it was one guitar.
I tried its solid-body brother yesterday, the J-Standard Iliad. I would have bought it if I had gelled with the neck (a pretty chunky U), but I just didn’t. But overall it was gorgeous, really high quality, and ticked all the boxes except neck feel:
The Fender Hybrid II I have landed on so far (if I decide to get one):
Just overall amazing feel and quality. Same colors as my Hybrid II P-Bass. And probably made by FujiGen too
I didn’t get to sit down with a MIJ Bacchus or Momose (the Momose are a bit out of my price range as well). Still want to check the Black Smokers too, but same price issue.
My other criteria I have’t really mentioned - it’s highly likely that if I get one I will be replacing the neck pup with either a P90 or a humbucker. The Hybrid II is routed for this which is a big plus.
Sounds like a winner. Which colors do they have?
Which one? The Fender or Fujigen?
Fender Hybrid II. It matches nice with the bass 
I know! I love it. If I get it I’ll have twins
Here’s all the stock colors. Some really good ones. There’s also some Factory Special Runs and also vendor specific ones but none are super special that I have seen yet.
US Blonde (not this pink in person, bummer)
Vintage Natural
Arctic White
Forest Blue/Rosewood
Forest Blue/Maple
Modena Red/Rosewood
Modena Red/Maple
Black
Burst/Rosewood
Burst/Maple
My Forest Blue P-Bass for reference
I like the red and blue maple. Artic white with the dark fretboard is nice too. Vintage and the blonde I would have to see irl. So many choices 
